Waqtiga Gaaban ee Hogaaminta ee Dhismaha Darajada Shiinaha Soosaarka Kiimikada HPMC Hydroxypropyl Methyl Cellulose HPMC
1st aad u fiican, iyo macmiilkeena macmiilka ayaa ah in aan u gaarsiino bixiyaha ku habboon rajooyinkayaga .Waxaa aan raadineynay intii karaankeena ah ee dhoofinta ugu waxtarka badan ee aan la kulminno wax badan Shiinaha ayaa soo saara kiimikada HPMCOxypropyl byluyl bylulose HPMC, waxaan kugu dhiirigelinaynaa inaad sameyso si aad uhesho sida aan u raadineynay la-hawlgalayaasha gudaha maraakiibtayada gudaha.Waxaan hubnaa inaad naga heli doontid ganacsi ganacsi oo nala socda oo kaliya maaha mid midho dhal leh laakiin sidoo kale faa'iido leh.Dhammaanteen waxaan diyaar u nahay inaan ku siinno waxaad u baahan tahay.
1aad aad u fiican,iyo Macmiil Sare waa hageheena si aan u gaarsiino bixiyaha ugu fiican rajadayadaShiinaha HPMC iyo Hydroxypropyl Methyl Cellulose, Waxaan qaadanay farsamada iyo maamulka nidaamka tayada, oo ku salaysan "macmiilka hanuunin, sumcad marka hore, faa'iido wadaaga, horumarinta dadaalka wadajirka ah", soo dhaweyn saaxiibada si ay ula xiriiraan oo iskaashi ka adduunka oo dhan.
Sharaxaada Alaabta
Hydroxypropyl Methyl Cellulose (HPMC)
Qaanuunka molecular
Hypromellose (Hydroxypropylmethylcellulose: HPMC) beddelka nooca 2910, 2906, 2208 (USP)
Guryaha Jirka
- budo cad oo cad ama huruud ah
- Ku milmay dareere organic ama aqueous qasan
- Samaynta filim hufan marka dareeraha laga saaro
- Wax fal-celin kiimikaad ah ma leh daroogada sababtoo ah hantideeda aan-ionic ahayn
- Miisaanka Molecular: 10,000 ~ 1,000,000
- Gel dhibic: 40 ~ 90 ℃
- Barta shidista tooska ah: 360 ℃
Hydroxypropyl Methylcellulose (HPMC) Farmashiisku waa Heerarka Dawada Hypromellose iyo kaabis, kaas oo loo isticmaali karo sidii dhumuc, kala-firdhiye, emulsifier iyo wakiilka filim-samaynta.
QualiCell Cellulose ether waxay ka kooban tahay methyl cellulose (USP, EP,BP,CP) iyo saddex nooc oo beddelka ah ee hydroxypropyl methyl cellulose (hypromellose USP, EP, BP, CP) mid kasta oo la heli karo dhowr darajooyin kala duwan in viscosity.HPMC alaabta waxaa laga soo qaatay dabiiciga ah la safeeyey. suufka suufka ah iyo saxarka alwaax, buuxinaya dhammaan shuruudaha USP, EP, BP, oo ay la socdaan Shahaadooyinka Kosher iyo Xalaal.
Habka wax-soo-saarka, suufka dabiiciga ah ee aadka loo sifeeyay waxaa lagu nadiifiyaa methyl chloride ama isku darka methyl chloride iyo propylene oxide si loo sameeyo biyo-milmi kara, eter-ka cellulose aan-ionic ahayn.Ma jiraan wax xoolo ah oo loo isticmaalo soo saarista HPMC.HPMC waxa loo isticmaali karaa xidhe ahaan foomamka qiyaasta qiyaasta adag sida kiniiniyada iyo granules.Waxa kale oo ay u adeegtaa hawlo kala duwan, tusaale ahaan, kor u qaadida haynta biyaha, dhumucda, u dhaqmidda sida kolloid ilaalin ah sababtoo ah dhaqdhaqaaqa dusha sare, sii daynta joogtada ah, iyo samaynta filimada.
QualiCell HPMC waxay bixisaa hawlo kala duwan sida haynta biyaha, kolloid ilaalinta, dhaqdhaqaaqa dusha sare, sii daynta joogtada ah.Waa iskudhis aan-ionic ahayn oo adkaysi u leh inay milixdu soo baxdo oo ku xasilo inta u dhaxaysa pH-ballaaran.Codsiyada caadiga ah ee HPMC waxay ku xidhaan foomamka qiyaasta qiyaasta adag sida kiniiniyada iyo granules ama dhumucyada codsiyada dareeraha ah.
Pharma HPMC waxay u dhaxaysaa 3 ilaa 200,000 cps, waxaana si balaadhan loogu isticmaali karaa daahan kiniiniga ah, granulation, binder, dhumuc weyn, xasiliye iyo samaynta kaabsulka HPMC qudaarta.
Tilmaamaha Kiimikada
| Hypromellose Tilmaamid | 60E (2910) | 65F ( 2906) | 75K (2208) |
| Heerkulka jel (℃) | 58-64 | 62-68 | 70-90 |
| Methoxy (WT%) | 28.0-30.0 | 27.0-30.0 | 19.0-24.0 |
| Hydroxypropoxy (WT%) | 7.0-12.0 | 4.0-7.5 | 4.0-12.0 |
| Viscosity (cps, 2% Xalka) | 3, 5, 6, 15, 50, 100, 400,4000, 10000, 40000, 60000, 100000, 150000, 200000 | ||
Heerka Alaabta
| Hypromellose Tilmaamid | 60E (2910) | 65F ( 2906) | 75K (2208) |
| Heerkulka jel (℃) | 58-64 | 62-68 | 70-90 |
| Methoxy (WT%) | 28.0-30.0 | 27.0-30.0 | 19.0-24.0 |
| Hydroxypropoxy (WT%) | 7.0-12.0 | 4.0-7.5 | 4.0-12.0 |
| Viscosity (cps, 2% Xalka) | 3, 5, 6, 15, 50, 100, 400,4000, 10000, 40000, 60000, 100000, 150000, 200000 | ||
Codsiga
Fasalka Pharma HPMC waxa uu awood u leeyahay soo saarista qaabaynta siidaynta la kantaroolay iyada oo la fududaynayo habka aadka loo isticmaalo kiniinka xidhidhiyaha.Fasalka Pharma wuxuu bixiyaa qulqulka budada wanaagsan, lebbiska tusmada, iyo isku-buufinta, taasoo ka dhigaysa inay si fiican ugu habboon yihiin cadaadis toos ah.
| Codsiga Pharma Excipients | Heerka Pharma HPMC | Qiyaasta |
| Bulk Laxative | 75K4000,75K100000 | 3-30% |
| Kareemada, jel | 60E4000,75K4000 | 1-5% |
| Diyaarinta Indhaha | 60E4000 | 01.-0.5% |
| Diyaarinta Dhibcaha Indhaha | 60E4000 | 0.1-0.5% |
| Wakiilka Joojinta | 60E4000, 75K4000 | 1-2% |
| Antacids | 60E4000, 75K4000 | 1-2% |
| Kiniinnada Binder | 60E5, 60E15 | 0.5-5% |
| Convention Qoyan Granulation | 60E5, 60E15 | 2-6% |
| Dahaarka kiniinka | 60E5, 60E15 | 0.5-5% |
| Matrix siidaynta la xakameeyey | 75K100000,75K15000 | 20-55% |
Tilmaamaha iyo Faa'iidooyinka
- Waxay hagaajisaa sifooyinka socodka alaabta
- Waxay yaraysaa waqtiyada habaynta
- La mid ah, profiles kala diri deggan
-Waxay wanaajisaa isku midnimada nuxurka
- Waxay dhimaysaa kharashka wax soo saarka
- Waxay xajistaa awoodda xajinta ka dib habka labajibbaaran ee is-jiidashada
Baakadaha
Xirmooyinka caadiga ah waa 25kg/durbaan
20'FCL: 9 tan oo paletteed leh;10 ton oo aan miir lahayn.
40'FCL: 18 tan oo leh palletized;20 ton oo aan loo dulqaadan karin. Waqti loogu talagalay Fasalka Dhismaha Shiinaha waxeey soo saartaa kiimikada HPMC hydroxypropyl bylulose cell bylulose HPMC, waxaan kugu dhiirigelinaynaa inaad sameyso sida aan u helno sidii aan u raadineynay la-hawlgalayaasha gudaha hawsha.Waxaan hubnaa inaad naga heli doontid ganacsi ganacsi oo nala socda oo kaliya maaha mid midho dhal leh laakiin sidoo kale faa'iido leh.Dhammaanteen waxaan diyaar u nahay inaan ku siinno waxaad u baahan tahay.
Waqtiga Hogaaminta oo GaabanShiinaha HPMC iyo Hydroxypropyl Methyl Cellulose, Waxaan qaadanay farsamada iyo maamulka nidaamka tayada, oo ku salaysan "macmiilka hanuunin, sumcad marka hore, faa'iido wadaaga, horumarinta dadaalka wadajirka ah", soo dhaweyn saaxiibada si ay ula xiriiraan oo iskaashi ka adduunka oo dhan.
