Goobaha warshadeed ee HPMC Hypromellose E5, E6, E15, E50 ee Kiniinka iyo Dahaarka
Waxaan had iyo jeer ku siinnaa adeegyada iibsadaha ugu damiirka badan, iyo noocyada ugu ballaaran ee nashqadaha iyo qaababka leh agabka ugu wanaagsan. Dadaalladan waxaa ka mid ah helitaanka nashqado la habeeyay oo leh xawaare iyo diris loogu talagalay Goobaha Warshadda ee HPMC Hypromellose E5, E6, E15, E50 ee Tablet iyo Coating alaabtayada tayada sare waa mid joogto ah oo sumcad leh xalalkeenana waa kuwa ugu iibinta badan gurigaaga iyo dibaddaba.
Waxaan had iyo jeer ku siinnaa adeegyada iibsadaha ugu damiirka badan, iyo noocyada ugu ballaaran ee nashqadaha iyo qaababka leh agabka ugu wanaagsan. Dadaalladan waxaa ka mid ah helitaanka nashqado la habeeyey oo leh xawaare iyo dirisShiinaha Hydroxypropyl Methyl Cellulose iyo HPMC, Hadda waxaan haynaa koox aad u fiican oo bixisa adeeg takhasus leh, jawaab degdeg ah, gaarsiinta waqtiga, tayada ugu fiican iyo qiimaha ugu fiican ee macaamiisheena. Ku qanacsanaanta iyo ammaanta wanaagsan ee macmiil kasta waa mudnaantayada. Waxaan si daacad ah u rajeyneynay inaan la shaqeyno macaamiisha adduunka oo dhan. Waxaan aaminsanahay inaan ku qanci karno. Waxaan sidoo kale si diiran u soo dhaweyneynaa macaamiisha inay soo booqdaan shirkadeena oo ay iibsadaan xalalkayaga.
Sharaxaada Alaabta
Hydroxypropyl Methyl Cellulose (HPMC)
Qaanuunka molecular
Hypromellose (Hydroxypropylmethylcellulose: HPMC) beddelka nooca 2910, 2906, 2208 (USP)
Guryaha Jirka
- budo cad oo cad ama huruud ah
- Ku milmay dareere organic ama aqueous qasan
- Samaynta filim hufan marka dareeraha laga saaro
- Wax fal-celin kiimikaad ah ma leh daroogada sababtoo ah hantideeda aan-ionic ahayn
- Miisaanka Molecular: 10,000 ~ 1,000,000
- Gel dhibic: 40 ~ 90 ℃
- Barta shidista tooska ah: 360 ℃
Hydroxypropyl Methylcellulose (HPMC) Farmashiyuutareedka darajada daawada waa Hypromellose daawo kaabista iyo kabka, kaas oo loo isticmaali karo sidii dhumuc, kala firdhiyey, emulsifier iyo wakiilka filim samaynta.
QualiCell Cellulose ether waxay ka kooban tahay methyl cellulose (USP, EP,BP,CP) iyo saddex nooc oo beddelka ah ee hydroxypropyl methyl cellulose (hypromellose USP, EP, BP, CP) mid kasta oo la heli karo dhowr darajooyin kala duwan in viscosity.HPMC alaabta waxaa laga soo qaatay dabiiciga ah la safeeyey. suufka suufka iyo saxarka alwaax, buuxinaya dhammaan shuruudaha USP, EP, BP, oo ay la socdaan Koosher iyo Shahaadooyin Xalaal ah.
Habka wax-soo-saarka, suufka dabiiciga ah ee aadka loo sifeeyay waxaa lagu nadiifiyaa methyl chloride ama isku darka methyl chloride iyo propylene oxide si loo sameeyo biyo-milmi kara, eter-ka cellulose aan-ionic ahayn. Ma jiro wax xoolo ah oo loo isticmaalo soo saarista HPMC.HPMC waxa loo isticmaali karaa xidhe ahaan foomamka qiyaasta qiyaasta adag sida kiniiniyada iyo granules. Waxa kale oo ay u adeegtaa hawlo kala duwan, tusaale ahaan, kor u qaadida haynta biyaha, dhumucda, u dhaqmidda sida kolloid ilaalin ah sababtoo ah dhaqdhaqaaqa dusha sare, sii daynta joogtada ah, iyo samaynta filimada.
QualiCell HPMC waxay bixisaa hawlo kala duwan sida haynta biyaha, kolloid ilaalinta, dhaqdhaqaaqa dusha sare, sii daynta joogtada ah. Waa iskudhis aan-ionic ahayn oo adkaysi u leh inay milixdu soo saarto oo ku xasilo inta u dhaxaysa pH-ballaaran. Codsiyada caadiga ah ee HPMC waxay ku xidhaan foomamka qiyaasta qiyaasta adag sida kiniiniyada iyo granules ama dhumucyada codsiyada dareeraha ah.
Pharma HPMC waxay u dhaxaysaa 3 ilaa 200,000 cps, waxaana si balaadhan loogu isticmaali karaa daahan kiniiniga ah, granulation, binder, dhumuc weyn, xasiliye iyo samaynta kaabsulka HPMC qudaarta.
Tilmaamaha Kiimikada
Hypromellose Tilmaamid | 60E (2910) | 65F ( 2906) | 75K (2208) |
Heerkulka jel (℃) | 58-64 | 62-68 | 70-90 |
Methoxy (WT%) | 28.0-30.0 | 27.0-30.0 | 19.0-24.0 |
Hydroxypropoxy (WT%) | 7.0-12.0 | 4.0-7.5 | 4.0-12.0 |
Viscosity (cps, 2% Xalka) | 3, 5, 6, 15, 50, 100, 400,4000, 10000, 40000, 60000, 100000, 150000, 200000 |
Heerka Alaabta
Hypromellose Tilmaamid | 60E (2910) | 65F ( 2906) | 75K (2208) |
Heerkulka jel (℃) | 58-64 | 62-68 | 70-90 |
Methoxy (WT%) | 28.0-30.0 | 27.0-30.0 | 19.0-24.0 |
Hydroxypropoxy (WT%) | 7.0-12.0 | 4.0-7.5 | 4.0-12.0 |
Viscosity (cps, 2% Xalka) | 3, 5, 6, 15, 50, 100, 400,4000, 10000, 40000, 60000, 100000, 150000, 200000 |
Codsiga
Pharma Grade HPMC waxa ay awood u siinaysaa soo saarista qaabaynta la xakameeyey iyada oo la fududaynayo habka ugu badan ee loo isticmaalo kiniinka xidhidhiyaha. Fasalka Pharma wuxuu bixiyaa qulqulka budada wanaagsan, lebbiska tusmada, iyo isku-buufinta, taasoo ka dhigaysa inay si fiican ugu habboon yihiin cadaadis toos ah.
Codsiga Pharma Excipients | Heerka Pharma HPMC | Qiyaasta |
Bulk Laxative | 75K4000,75K100000 | 3-30% |
Kareemada, jel | 60E4000,75K4000 | 1-5% |
Diyaarinta Indhaha | 60E4000 | 01.-0.5% |
Diyaarinta Dhibcaha Indhaha | 60E4000 | 0.1-0.5% |
Wakiilka Joojinta | 60E4000, 75K4000 | 1-2% |
Antacids | 60E4000, 75K4000 | 1-2% |
Kiniinnada Binder | 60E5, 60E15 | 0.5-5% |
Convention Qoyan Granulation | 60E5, 60E15 | 2-6% |
Dahaarka kiniinka | 60E5, 60E15 | 0.5-5% |
Matrix siidaynta la xakameeyey | 75K100000,75K15000 | 20-55% |
Tilmaamaha iyo Faa'iidooyinka
- Waxay hagaajisaa sifooyinka socodka alaabta
- Waxay yaraysaa waqtiyada habaynta
- La mid ah, profiles kala diri deggan
- Waxay wanaajisaa isku midnimada nuxurka
- Waxay dhimaysaa kharashka wax soo saarka
- Waxay xajistaa awoodda xajinta ka dib habka labajibbaaran ee is-jiidashada
Baakadaha
Xirmooyinka caadiga ah waa 25kg/durbaan
20'FCL: 9 tan oo leh paletteed; 10 ton oo aan miir lahayn.
40'FCL: 18 tan oo leh palletized; 20 ton unpalletized. Waxaan had iyo jeer ku siinaynaa adeegyada iibsadaha ugu damiirka leh, iyo noocyada kala duwan ee ugu ballaaran ee nashqadaha iyo qaababka leh qalabka ugu fiican. Dadaalladan waxaa ka mid ah helitaanka nashqado la habeeyay oo leh xawaare iyo diris loogu talagalay Goobaha Warshadda ee HPMC Hypromellose E5, E6, E15, E50 ee Tablet iyo Coating alaabtayada tayada sare waa mid joogto ah oo sumcad leh xalalkeenana waa kuwa ugu iibinta badan gurigaaga iyo dibaddaba.
Goobaha warshadeed eeShiinaha Hydroxypropyl Methyl Cellulose iyo HPMC, Hadda waxaan haynaa koox aad u fiican oo bixisa adeeg takhasus leh, jawaab degdeg ah, gaarsiinta waqtiga, tayada ugu fiican iyo qiimaha ugu fiican ee macaamiisheena. Ku qanacsanaanta iyo ammaanta wanaagsan ee macmiil kasta waa mudnaantayada. Waxaan si daacad ah u rajeyneynay inaan la shaqeyno macaamiisha adduunka oo dhan. Waxaan aaminsanahay inaan ku qanci karno. Waxaan sidoo kale si diiran u soo dhaweyneynaa macaamiisha inay soo booqdaan shirkadeena oo ay iibsadaan xalalkayaga.