Qalabka Dhismaha ee ugu iibinta Fiican ee Cellulose Ether HEC Hemc HPMC ee Heerka Warshadaha Dhismaha
Had iyo jeer waa in la xoojiyo oo la xoojiyo adeegga ugu fiican iyo adeegga xalalka hadda jira, isla markaana si joogto ah u horumariyo alaabooyin cusub si ay u daboolaan baahida macaamiisha gaarka ah ee Qalabka Dhismaha Qalabka Cellulose Ether HEC Hemc HPMC ee Heerka Warshadaha Dhismaha, Si loo gaaro faa'iidooyinka isdhaafsiga , Ganacsigeena ayaa si ballaaran u kobcinaya tabahayada caalimiyeynta marka la eego isgaarsiinta macaamiisha dibadda, si degdeg ah u gaarsiinta, ugu sarreeya iyo iskaashiga muddada dheer.
Had iyo jeer waxaan diirada saarnaa inaan xoojino oo aan kor u qaadno tayada wanaagsan iyo adeegga xalalka hadda jira, inta lagu guda jiro si joogto ah u soo saara alaabooyin cusub si loo daboolo baahiyaha macaamiisha gaarka ahShiinaha HPMC iyo Hydroxypropyl Methyl Cellulose, Badeecadahayaga waxaa loo dhoofiyaa adduunka oo dhan. Macaamiishayadu waxay had iyo jeer ku qanacsan yihiin tayadayada la isku halayn karo, adeegyada macaamiisha ku jihaysan iyo qiimaha tartanka. Hadafkayagu waa "inaan sii wadno si aan u kasbano daacadnimadaada anagoo u hurayna dadaalkeena horumarinta joogtada ah ee alaabtayada iyo adeegyadayada si aan u hubinno qanacsanaanta isticmaalayaashayada, macaamiisheena, shaqaalaha, alaab-qeybiyeyaasha iyo bulshooyinka caalamka ee aan iska kaashano".
Sharaxaada Alaabta
Hydroxypropyl Methyl Cellulose (HPMC)
Qaanuunka molecular
Hypromellose (Hydroxypropylmethylcellulose: HPMC) beddelka nooca 2910, 2906, 2208 (USP)
Guryaha Jirka
- budo cad oo cad ama huruud ah
- Ku milmay dareere organic ama aqueous qasan
- Samaynta filim hufan marka dareeraha laga saaro
- Wax fal-celin kiimikaad ah ma leh daroogada sababtoo ah hantideeda aan-ionic ahayn
- Miisaanka Molecular: 10,000 ~ 1,000,000
- Gel dhibic: 40 ~ 90 ℃
- Barta shidista tooska ah: 360 ℃
Hydroxypropyl Methylcellulose (HPMC) Farmashiyuutareedka darajada daawada waa Hypromellose daawo kaabista iyo kabka, kaas oo loo isticmaali karo sidii dhumuc, kala firdhiyey, emulsifier iyo wakiilka filim samaynta.
QualiCell Cellulose ether waxay ka kooban tahay methyl cellulose (USP, EP,BP,CP) iyo saddex nooc oo beddelka ah ee hydroxypropyl methyl cellulose (hypromellose USP, EP, BP, CP) mid kasta oo la heli karo dhowr darajooyin kala duwan in viscosity.HPMC alaabta waxaa laga soo qaatay dabiiciga ah la safeeyey. suufka suufka iyo saxarka alwaax, buuxinaya dhammaan shuruudaha USP, EP, BP, oo ay la socdaan Koosher iyo Shahaadooyin Xalaal ah.
Habka wax-soo-saarka, suufka dabiiciga ah ee aadka loo sifeeyay waxaa lagu nadiifiyaa methyl chloride ama isku darka methyl chloride iyo propylene oxide si loo sameeyo biyo-milmi kara, eter-ka cellulose aan-ionic ahayn. Ma jiro wax xoolo ah oo loo isticmaalo soo saarista HPMC.HPMC waxa loo isticmaali karaa xidhe ahaan foomamka qiyaasta qiyaasta adag sida kiniiniyada iyo granules. Waxa kale oo ay u adeegtaa hawlo kala duwan, tusaale ahaan, kor u qaadida haynta biyaha, dhumucda, u dhaqmidda sida kolloid ilaalin ah sababtoo ah dhaqdhaqaaqa dusha sare, sii daynta joogtada ah, iyo samaynta filimada.
QualiCell HPMC waxay bixisaa hawlo kala duwan sida haynta biyaha, kolloid ilaalinta, dhaqdhaqaaqa dusha sare, sii daynta joogtada ah. Waa iskudhis aan-ionic ahayn oo adkaysi u leh inay milixdu soo baxdo oo ku xasilo inta u dhaxaysa pH-ballaaran. Codsiyada caadiga ah ee HPMC waxay ku xidhaan foomamka qiyaasta qiyaasta adag sida kiniiniyada iyo granules ama dhumucyada codsiyada dareeraha ah.
Pharma HPMC waxay u dhaxaysaa 3 ilaa 200,000 cps, waxaana si balaadhan loogu isticmaali karaa daahan kiniiniga ah, granulation, binder, dhumuc weyn, xasiliye iyo samaynta kaabsulka HPMC qudaarta.
Tilmaamaha Kiimikada
Hypromellose Tilmaamid | 60E (2910) | 65F ( 2906) | 75K (2208) |
Heerkulka jel (℃) | 58-64 | 62-68 | 70-90 |
Methoxy (WT%) | 28.0-30.0 | 27.0-30.0 | 19.0-24.0 |
Hydroxypropoxy (WT%) | 7.0-12.0 | 4.0-7.5 | 4.0-12.0 |
Viscosity (cps, 2% Xalka) | 3, 5, 6, 15, 50, 100, 400,4000, 10000, 40000, 60000, 100000, 150000, 200000 |
Heerka Alaabta
Hypromellose Tilmaamid | 60E (2910) | 65F ( 2906) | 75K (2208) |
Heerkulka jel (℃) | 58-64 | 62-68 | 70-90 |
Methoxy (WT%) | 28.0-30.0 | 27.0-30.0 | 19.0-24.0 |
Hydroxypropoxy (WT%) | 7.0-12.0 | 4.0-7.5 | 4.0-12.0 |
Viscosity (cps, 2% Xalka) | 3, 5, 6, 15, 50, 100, 400,4000, 10000, 40000, 60000, 100000, 150000, 200000 |
Codsiga
Pharma Grade HPMC waxa ay awood u siinaysaa soo saarista qaabaynta la xakameeyey iyada oo la fududaynayo habka ugu badan ee loo isticmaalo kiniinka xidhidhiyaha. Fasalka Pharma wuxuu bixiyaa qulqulka budada wanaagsan, lebbiska tusmada, iyo isku-buufinta, taasoo ka dhigaysa inay si fiican ugu habboon yihiin cadaadis toos ah.
Codsiga Pharma Excipients | Heerka Pharma HPMC | Qiyaasta |
Bulk Laxative | 75K4000,75K100000 | 3-30% |
Kareemada, jel | 60E4000,75K4000 | 1-5% |
Diyaarinta Indhaha | 60E4000 | 01.-0.5% |
Diyaarinta Dhibcaha Indhaha | 60E4000 | 0.1-0.5% |
Wakiilka Joojinta | 60E4000, 75K4000 | 1-2% |
Antacids | 60E4000, 75K4000 | 1-2% |
Kiniinnada Binder | 60E5, 60E15 | 0.5-5% |
Convention Qoyan Granulation | 60E5, 60E15 | 2-6% |
Dahaarka kiniinka | 60E5, 60E15 | 0.5-5% |
Matrix siidaynta la xakameeyey | 75K100000,75K15000 | 20-55% |
Tilmaamaha iyo Faa'iidooyinka
- Waxay hagaajisaa sifooyinka socodka alaabta
- Waxay yaraysaa waqtiyada habaynta
- La mid ah, profiles kala diri deggan
- Waxay wanaajisaa isku midnimada nuxurka
- Waxay dhimaysaa kharashka wax soo saarka
- Waxay xajistaa awoodda xajinta ka dib habka labajibbaaran ee is-jiidashada
Baakadaha
Xirmooyinka caadiga ah waa 25kg/durbaan
20'FCL: 9 tan oo leh paletteed; 10 ton oo aan miir lahayn.
40'FCL: 18 tan oo leh palletized; 20 ton unpalletized.Our diiradda on had iyo jeer waa in la xoojiyo iyo kor loogu qaado u fiican iyo adeegga xalalka hadda, in ka hor si joogto ah u horumariyaan alaabta cusub si ay u daboolaan baahida macaamiisha kala duwan 'ee iibka ugu Wanaagsan Dhismaha Material Cellulose Ether HEC Hemc HPMC ee Dhismaha Warshadaha, Si loo gaaro faa'iidooyinka isdhaafsiga ah, ganacsigeenu wuxuu si ballaaran u kobcinayaa tabahayada caalamiyeynta marka loo eego isgaarsiinta macaamiisha dibadda, si degdeg ah u gaarsiinta, ugu fiican iyo iskaashiga muddada dheer.
Iibinta ugu WanaagsanShiinaha HPMC iyo Hydroxypropyl Methyl Cellulose, Badeecadahayaga waxaa loo dhoofiyaa adduunka oo dhan. Macaamiishayadu waxay had iyo jeer ku qanacsan yihiin tayadayada la isku halayn karo, adeegyada macaamiisha ku jihaysan iyo qiimaha tartanka. Hadafkayagu waa "inaan sii wadno si aan u kasbano daacadnimadaada anagoo u hurayna dadaalkeena horumarinta joogtada ah ee alaabtayada iyo adeegyadayada si aan u hubinno qanacsanaanta isticmaalayaashayada, macaamiisheena, shaqaalaha, alaab-qeybiyeyaasha iyo bulshooyinka caalamka ee aan iska kaashano".