Hydroxypropyl methylcellulose (HPMC) runtii waa isku-dhismeed badan oo caadi ahaan loo isticmaalo dhumuc ahaan warshadaha kala duwan.
1. Hordhac HPMC:
Hydroxypropyl methylcellulose (HPMC) waa polymer synthetic oo ka soo jeeda cellulose, taas oo ah qaybta ugu muhiimsan ee dhismaha derbiyada unugyada dhirta. HPMC waa eter cellulose kiimiko ahaan wax laga beddelay, halkaas oo kooxaha hydroxyl ee laf dhabarta cellulose lagu beddelay kooxaha methyl iyo hydroxypropyl labadaba. Wax ka beddelkaani wuxuu kor u qaadayaa milanka biyaha iyo xasilloonida cellulose, taasoo ka dhigaysa mid ku habboon codsiyo badan oo warshadeed.
2. Guryaha HPMC:
HPMC waxay leedahay siyaalo dhowr ah oo ka dhigaya wakiilka dhumuc ee ku habboon:
a. Biyo Solubility: HPMC waxa ay muujisaa milmi-biyood aad u fiican, samaynta xalal cad marka lagu milmo biyaha. Hantidani waxay lama huraan u tahay isticmaalkeeda hababka kala duwan ee aqueous.
b. Xasiloonida pH: HPMC waxa ay ku haysaa astaamaheeda dhumucdi badan oo kala duwan pH, taas oo ka dhigaysa mid ku haboon codsiyada jawi acidic, dhexdhexaad ah, iyo alkaline.
c. Xasilloonida kulaylka: HPMC waa mid degan heerkulka sare, taas oo u ogolaanaysa in loo isticmaalo hababka kuleylinta inta lagu jiro wax soo saarka.
d. Kartida Samaynta Filimada: HPMC waxay samayn kartaa filimo dabacsan oo hufan marka la qalajiyo, kuwaas oo ka hela codsiyada dahaarka, filimada, iyo kiniiniyada dawooyinka.
e. Xakamaynta Rheological: HPMC waxay wax ka bedeli kartaa viscosity iyo rheological dhaqanka xalalka, siinta xakamaynta sifooyinka socodka qaabaynta.
3. Habka wax soo saarka ee HPMC:
Habka wax soo saarka ee HPMC waxay ku lug leedahay dhowr tillaabo:
a. Daawaynta Alkali: Cellulose waxaa marka hore lagu daaweeyaa xal alkaline ah, sida sodium hydroxide, si loo carqaladeeyo curaarta hydrogen ee u dhaxaysa silsiladaha cellulose iyo bararin fiilooyinka cellulose.
b. Etherification: Methyl chloride iyo propylene oxide ayaa markaas lagu falceliyaa cellulose iyadoo lagu jiro xaalado la xakameynayo si loogu soo bandhigo kooxaha methyl iyo hydroxypropyl ee lafaha cellulose, taasoo keentay HPMC.
c. Nadiifinta: Badeecada HPMC ee cayriin waa la nadiifiyey si looga saaro kiimikooyinka iyo wasakhda aan la falgelin, taasoo keenta budada HPMC ee nadiifka ah ama granules.
4. Codsiyada HPMC sidii dhumuc ahaan:
HPMC waxay ka heshaa isticmaalka baahsan sida wakiilka dhumuc ee warshadaha kala duwan:
a. Warshadaha Dhismaha: Agabka dhismaha sida hoobiyeyaasha sibidhka, HPMC waxay u shaqaysaa sidii dhumuc iyo biyo haynta, wanaajinta karti-shaqsiyeedka iyo ku dhegganaanta hoobiye.
b. Warshadaha cuntada: HPMC waxa loo isticmaalaa sidii dhumuc iyo xasiliye ee alaabta cuntada sida suugada, maraqyada, iyo macmacaanka, bixinta viscosity iyo horumarinta texture.
c. Warshadaha Daawooyinka: Qaababka dawooyinka sida kaniiniyada iyo ka joojinta, HPMC waxay u adeegtaa sidii walax xidhe iyo dhumuc, fududaynta qaybinta lebis ee maaddooyinka firfircoon.
d. Alaabooyinka Daryeelka Shakhsi ahaaneed: HPMC waxaa lagu dhex daray waxyaalaha la isku qurxiyo iyo alaabta daryeelka shakhsi ahaaneed sida labeennada, kiriimyada, iyo shaambooyinka si loo bixiyo viscosity, kor loogu qaado xasilloonida, loona hagaajiyo qaab-dhismeedka.
e. Rinjiyeynta iyo Dahaarka: HPMC waxaa lagu daraa rinjiyada, dahaarka, iyo xabagta si loo xakameeyo viscosity, looga hortago hoos u dhaca, iyo kor loogu qaado samaynta filimada.
Hydroxypropyl methylcellulose (HPMC) waa wakiil dhumuc badan leh oo leh codsiyo kala duwan oo warshado kala duwan ah. Sifooyinkeeda gaarka ah, oo ay ku jiraan milanka biyaha, xasilloonida pH, xasilloonida kulaylka, kartida samaynta filimada, iyo xakamaynta rheological, waxay ka dhigtaa shay lagama maarmaan u ah qaabab badan. Laga soo bilaabo alaabta dhismaha ilaa alaabta cuntada, daawooyinka, alaabta daryeelka shakhsi ahaaneed, iyo dahaarka, HPMC waxay door muhiim ah ka ciyaartaa kor u qaadista tayada iyo tayada alaabta. Fahamka sifooyinka iyo codsiyada HPMC waxay lama huraan u tahay hab-sameeyayaasha iyo soo saarayaasha doonaya inay hagaajiyaan habayntooda oo ay daboolaan baahiyaha macaamiisha.
Waqtiga boostada: Mar-08-2024